Pulmonary cancers

Almost all primary lung cancers are bronchial carcinomas. Mets from BBBB places usually develop in the parenchyma and are relatively asymptomatic even when mets are extensive.

Small cell lung cancer

 * 1) AKA 'Oat-cell carcinoma', from enterochromaffin cell *Kulchitsky cells a part of amine precursor uptake and decarboxylation (APUD) endocrine system. APUD cells make polypeptides and amines which act as hormones or neurotransmitters.
 * 2) They are rapidly growing and highly malignant, spread early and almost always inoperable at presentation
 * 3) SCLC responds to chemo but have poor prognosis

Non-small cell lung cancer

 * 1) Squamous (most present as obstructive lesions of the bronchus leading to infection, local spread is common but mets occur late)
 * 2) Adenocarcinoma ( arise from mucous cells of bronchial epithelium, and is the most common bronchial cancer associated with ASBESTOS and is more common in NON-SMOKERS compared to other types)
 * 3) Large-cell (less differentiated forms of squamous and adenocarcinoma, these metastasize early)
 * 4) Carcionoid tumours
 * 5) Bronchoalveolar cell(occurs as peripheral solitary/diffuse nodular lesions)